21 patients with a severe course of COVID-19 were under observation. The study was carried out in a specialized hospital for the treatment of patients with coronavirus infection. A more detailed analysis of the ECG was carried out: the duration of the corrected QT interval, the variance of the QT interval, the Tp-Te interval and the Tp-Te/QT ratio were determined. Prolonged repolarization rates are a poor predictor of a dangerous COVID-19 outcome.
Any epidemic and pandemic that is a great stress or emergency leads to disruptions in the psycho-neurological system and human behavior. Psycho-emotional excitement in patients with severe Covid-19 dramatically reduces the effectiveness of non-invasive ventilation. Purpose of the study: to assess the efficacy, safety and impact on the quality of life of patients with dexmedetomidine and propofol against the background of a decrease in need for oxygen. The study included 21 patients with severe and extremely severe Covid-19. In the first group of patients with fear of death, a combination of drugs propofol + sibazone + fentanyl was used. In the second group, dexmedetomidine and promedol. Conclusions: in patients with a severe course of coronavirus infection, dexmedetomidine is more effective in reducing psycho neurological arousal and improving cognitive functions, which leads to an effective supply of oxygen and to their faster recovery.